Low-dose CT screening methods may prevent one death per 250 at-risk adults screened, according to a meta-analysis of eight randomised controlled clinical trials of lung cancer screening.
Researchers at the University of Georgia analysed the health outcomes of 90,275 patients, comparing those who were screened as opposed to those who received usual medical care or chest x-rays.
Their analysis found a clinically and statistically remarkable 0.4 per cent discount in lung cancer-caused death long term, which translates into one preventable death per 250 at-risk adults screened. The result of the analysis were published in the Annals of Circle of relatives Medicine.
The authors recognise the important potential harm of overdiagnosis in cancer screening programs, and there was once some evidence of overdiagnosis because of increased incidence in the screened group.
On the other hand, based on the discount in all-cause mortality being in the same direction and magnitude as lung cancer mortality, the authors interpret that the associated harms “do not appear to increase other causes of mortality,” and the result of the study align with the U.S. Preventive Services and products Task Force recommendations for CT-based lung cancer screenings for adults age 55 to 80 who have a history of steady smoking.
(This story has been published from a wire agency feed without modifications to the text.)
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