In a retrospective case study, Mayo Clinic researchers have found that antibiotics administered to children younger than two are associated with several ongoing illnesses or conditions, ranging from allergies to obesity.
The findings appear in Mayo Clinic Proceedings.
The use of health record data from the Rochester Epidemiology Project, population-based research collaboration in Minnesota and Wisconsin, researchers analyzed data from over 14,500 children.
Approximately 70 per cent of the children had received no less than one remedy with antibiotics for illness before age 2. Children receiving a couple of antibiotic treatments were much more likely to have a couple of illnesses or conditions later in childhood.
Types and frequency of illness varied depending on age, kind of medication, dose, and numerous doses. There also were some differences between girls and boys.
Conditions associated with early use of antibiotics included asthma, allergic rhinitis, weight issues and obesity, food allergies, attention deficit hyperactivity disorder, celiac disease, and atopic dermatitis.
The authors speculate that despite the fact that antibiotics may only transiently have an effect on the microbiome, the collection of microbes in the body, this may have long-term health consequences.
“We wish to emphasize that this study shows organization? not causation? of these conditions,” said Nathan LeBrasseur, PhD, a researcher at Mayo Clinic’s Robert and Arlene Kogod Center on Aging and the study’s senior writer.
“These findings offer the possibility to target future research to decide more dependable and safer approaches to timing, dosing and types of antibiotics for children in this age group,” added LeBrasseur.
While recent data show an increase in one of the childhood conditions involved in the study, experts don’t seem to be certain why. Other than the issue of multidrug resistance, antibiotics have been presumed secure by most paediatricians.
Researchers also say the final goal is to supply practical guidelines for physicians on the safest way to use antibiotics early in life.
(This story has been published from a wire agency feed without modifications to the text.)
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